وصف الكتاب | The present compendium on ‘Advanced Practical Medicinal Chemistry’ is designed specifically to serve as a text-cum-reference book not only intended for the advanced undergraduate and graduate students of Pharmacy specializing in pharmaceutical chemistry but also for the bulk-drug industrial researchers and academics who work intimately with medicinal compounds. It mainly comprises of four comprehensive chapters. First chapter is entirely devoted to ‘Safety in Chemical Laboratory’, which is an absolute must for each medicinal chemist. Second chapter is on ‘Drug Synthesis’ and concentrates on three vital aspects, namely: conceptualization of a synthesis, reaction variants and stereochemistry. Third chapter exclusively deals with ᾴPerforming the Reactions and entails the wide range of latest laboratory techniques used in a good chemical laboratory to facilitate synthesis of ‘drugsΐ. Fourth chapter is particularly focused and earmarked to ᾴSynthesis of Medicinal Compounds and essentially include various cardinal aspects, such as: types of chemical reactions, organic name reactions (ONRs) and selected medicinal compounds. A galaxy of ninety carefully chosen medicinal compounds have been presented in an original unique-style comprising of: Chemical structure, synonym (s)/chemical name (s)-theory chemicals required-procedure-precautions-recrystallization-theoretical yield/practical yield, physical parameters, uses and questions for viva-voce. |