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Antibody-Drug Conjugates: Methods and Protocols

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متوفر قريبا
نظرة عامة
المواصفات
الناشرHumana; 2020th edition
رقم الكتاب المعياري الدولي 139781493999316
رقم الكتاب المعياري الدولي 101493999311
الكاتبL Nathan Tumey
تنسيق الكتابPaperback
اللغةEnglish
وصف الكتابThis volume looks at key methodologies that are commonly used across antibody drug conjugates (ADCs) programs. The chapters in this book cover topics such as conjugations to endogenous cysteine residues; click chemistry conjugations; antibody conjugations via glycosyl remodeling; analysis of ADCs by native mass spectrometry; characterization of ADCs by capillary electrophoresis; LC/MS methods for studying lysosomal ADC catabolism; and determination of ADC concentration by ligand-binding assays. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and practical, Antibody-Drug Conjugates: Methods and Protocols is a valuable resource that aims to lower the activation barrier when undertaking a new discipline, and provides a toolbox for the next generation of ADC scientists.
LanguageEnglish
تاريخ النشر10/24/2020
عدد الصفحات373.0

Antibody-Drug Conjugates: Methods and Protocols

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