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- إرجاع مجاني بسهولة
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المواصفات
| الناشر | LAP Lambert Academic Publishing; Standard Edition |
| رقم الكتاب المعياري الدولي 13 | 9786205528082 |
| رقم الكتاب المعياري الدولي 10 | 6205528088 |
| الكاتب | Prasanta Kumar Biswal |
| اللغة | English |
| وصف الكتاب | Due to poor drug solubility and absorption, many drug candidates fall short of expectations. Self-emulsifying drug delivery methods increase the solubility and bioavailability of poorly soluble medications. When SEDDS are added to an aqueous phase and gently mixed, fine oil-in-water emulsions form. SEDDS come in soft or hard gelatin capsules for oral administration and form fine, stable oil-in-water emulsions. SEDDS are primarily manufactured as liquid formulations, which have poor stability and mobility, low drug loading, a limited number of dosage form options, irreversible drug/excipient precipitation, and a high proportion (30-60%) of surfactants that might irritate the gastrointestinal system. Solid-SEDDS has been studied to avoid the problems of liquid SEDDS. The adsorption of liquid self-micro-emulsified formulations on solid carriers is one of the best ways to create free-flowing powders for compression into tablet dosage form (SMET). |
| تاريخ النشر | 29 December 2022 |
| عدد الصفحات | 76 pages |
ATORVASTATIN SELF-EMULSIFIED TABLETS FORMULATION AND EVALUATION
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