How to use: Apply the gel or cream evenly with a thin layer on the affected skin once a day before bed (protecting the area around the eyes and lips). The medicine should be used on clean and dry skin. The therapeutic effect develops after 4-8 weeks of treatment, and sustained improvement - after 3 months from the start of treatment. Usually, treatment begins with the gel, with sensitive and dry skin, as well as in the fall and winter seasons, Differin cream, which contains moisturizing ingredients that appear in the skin.