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Production of -Lactam Antibiotics Through Penicillin V Acylase

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PublisherLAP Lambert Academic Publishing
ISBN 139783659317705
ISBN 103659317705
AuthorNaz Tooba
LanguageEnglish
Book DescriptionSemi-synthetic β-lactam antibiotics are the largest group of antibiotics used worldwide. Penicillin V Acylase (Cephalosporin acylase) is a crucial enzyme for the development of new enzymatic pathways leading to the production of semi-synthetic cephalosporins. 7-amino desacetoxy cephalosporanic acid (7-ADCA) is an important intermediate in these pathways. Large quantities of this compound are needed, but the traditional production routes are time-consuming, expensive and/or polluting.Pakistan being an agricultural country has potential resources of biomass for their exploitation in the manufacture of cell biomass, enzymes or microbial metabolites.
Publication Date2013-01-16
Number of Pages96 pages

Production of -Lactam Antibiotics Through Penicillin V Acylase

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