Publisher | Wiley-Blackwell |
ISBN 13 | 9780471329220 |
ISBN 10 | 0471329223 |
Author | Tse-Lok Ho |
Book Format | Hardcover |
Language | English |
Book Description | Chiral molecules come in "right-handed" or "left-handed" forms which look the same in 2D but are mirror images of each other. These molecules do not behave in the same way and react differently towards enzymes. A good example of this can be seen in Thalidomide where the "left-handed" molecule acts as a sedative but the "right-handed" molecule causes severe birth defects. Stereochemistry is the study of these molecules. This text should be of interest to chemists who are planning a synthesis. Organic chemists must choose the best methods for making the preferred form, and how to achieve this has become a focal point in organic synthesis research. The book uses examples from the synthetic literature to demonstrate how the basic principles of organic stereochemistry apply; is designed to present information in a concise and readable fashion; and it incorporates hundreds of reaction schemes. |
About the Author | TSE-LOK HO is Professor of Organic Chemistry at National Chiao Tung University in Taiwan. His research interests are in organic synthesis, including total synthesis of natural products and methodology. He has written 12 books, including, most recently, Stereoselectivity in Synthesis, available from Wiley. Dr. Ho holds degrees from National Taiwan University and the University of New Brunswick, Canada. |
Publication Date | 14 April 1999 |
Number of Pages | 352 |