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- استرجاع مجاني وسهل
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Drug-Like Properties Paperback English by Li Di, Edward H. Kerns - 2016
الآن:
924.15 د.إ.شامل ضريبة القيمة المضافة
توصيل مجاني
احصل عليه خلال 26 يناير
احصل على د.إ. 46.21 رصيد مسترجع باستخدام بطاقة بنك المشرق نون الائتمانية. اشترك الآن. قدّم الحين
1
توصيل مجاني لنقطة نون ومراكز الاستلام
معرفة المزيد
إرجاع سهل لكل المنتجات في هذا العرض.
شريك لنون منذ
2+ سنينالمواصفات
| الناشر | Elsevier |
| رقم الكتاب المعياري الدولي 13 | 9780128010761 |
| اللغة | الإنجليزية |
| وصف الكتاب | Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates. This valuable resource explores physiochemical properties, including solubility and permeability, before exploring how compounds are absorbed, distributed, and metabolized safely and stably. Review chapters provide context and underscore the importance of key concepts such as pharmacokinetics, toxicity, the blood-brain barrier, diagnosing drug limitations, prodrugs, and formulation. Building on those foundations, this thoroughly updated revision covers a wide variety of current methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties for process and product improvement. From conducting key assays for interpretation and structural analysis, the reader learns to implement modification methods and improve each ADME property. |
| تاريخ النشر | 2016 |
| عدد الصفحات | 580 |
Drug-Like Properties Paperback English by Li Di, Edward H. Kerns - 2016
تمت الإضافة لعربة التسوق
مجموع السلة 924.15 د.إ.
