Antibody-Drug Conjugates: Methods and Protocols
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Specifications
| Publisher | Humana; 2020th edition |
| ISBN 13 | 9781493999316 |
| ISBN 10 | 1493999311 |
| Author | L Nathan Tumey |
| Book Format | Paperback |
| Language | English |
| Book Description | This volume looks at key methodologies that are commonly used across antibody drug conjugates (ADCs) programs. The chapters in this book cover topics such as conjugations to endogenous cysteine residues; click chemistry conjugations; antibody conjugations via glycosyl remodeling; analysis of ADCs by native mass spectrometry; characterization of ADCs by capillary electrophoresis; LC/MS methods for studying lysosomal ADC catabolism; and determination of ADC concentration by ligand-binding assays. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and practical, Antibody-Drug Conjugates: Methods and Protocols is a valuable resource that aims to lower the activation barrier when undertaking a new discipline, and provides a toolbox for the next generation of ADC scientists. |
| Language | English |
| Publication Date | 10/24/2020 |
| Number of Pages | 373.0 |
Antibody-Drug Conjugates: Methods and Protocols
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