Superfoods For the MindBrain-Derived Neurotrophic Factor (BDNF) is a key neuroprotein associated with learning and memory. Scientists have noticed that BDNF and the brain’s ability to wire new connections decreases over time - an unfortunate result of aging. Neurofactor®, the extract of the little-known coffee fruit, has been shown to support healthy, replenished BDNF levels that promote mental clarity. Studies have also found special compounds in lion’s mane mushrooms that can stimulate the growth of brain cells. That’s why you’ll find both in every serving of Pure.